Levlen (Levonorgestrel and Ethinyl Estradiol)

Levlen contains 2 hormones: levonorgestrel and ethinyl estradiol able to suppress ovulation. This birth control means is produced to prevents pregnancy.

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Table of Contents


What is it?

Levlen is a combined birth control drug for oral administration with a low content of estrogen and gestagen. Ethinyl estradiol and levonorgestrel are active synthetic estrogen and gestagen (respectively). Inhibiting the production of FSH and LH, the drug prevents the maturation of the egg in the follicle and ovulation, as well as cyclic changes in the endometrium, disrupting its implantability. Practically does not prevent the occurrence of cyclical menstrual-like bleeding.

How to start using?

The schedule of contraceptive medications is similar to the schedules of other commonly used hormonal substances. Levlen is taken 1 tablet/day for 28 days. During the intake of inactive pills, the menstruation will start. At the beginning of use, after a long interval, or when changing COC, the first pill should be taken on the 1st day of the menstrual cycle. To ensure a constant content of hormones in the blood plasma, the interval between taking the next dose should not exceed 36 hours. The interval should vary, on average, at 22-26 hours.


Levlen pills are taken by following the indications given on the blister. Take the drug at the same time of day, starting from the first day of the monthly cycle, 1 tablet per day for 4 weeks (28 days). After that, there is no break, during which bleeding usually begins. The next cycle begins on the same day of the week as the previous one began.Levlen 28 Pills_ Control your Pregnancy and Cycle

Side effects

  • Dyspeptic phenomena;
  • Headaches;
  • Fatigue;
  • Instability of mood;
  • Increase or decrease in body weight;
  • The tension in the mammary glands;
  • Reduced glucose tolerance;
  • Changes in libido;
  • Spotting;
  • Uterine bleeding.

The poor spotting of blood from the vagina, resulting from the use of the drug, does not require drug discontinuation. If bleeding is more severe, you must stop taking the pills and conduct a gynecological examination.

Depending on the result, you can start a new 28-day course on the 5th day of menstruation. The frequency of bleeding decreases during subsequent courses of the drug, then they usually stop.

A common side effect of Levlen is skin rash.

Keep in mind that smoking can increase the incidence and severity of side effects.

Missed pill

The reliability of the drug may decrease if the patient forgot to take a pill containing levonorgestrel + ethinyl estradiol, and especially if the patient forgot to take the first pills from the blister.

If the delay in taking the drug was less than 12 hours, contraceptive reliability is not reduced. A woman should take a pill as soon as possible, the next pill is taken at the usual time.

If the missing of one or several pills is more than 12 hours, contraceptive reliability may be decreased.


In case of overdose, an organism reacts by the symptoms of dyspepsia or metrorrhagia. Medical science has not yet invented a specific antidote that could be applied in case of overdose. Treatment is prescribed depending on the symptoms in order to relieve them.


  • Pregnancy;
  • Hormone-dependent tumors of the mammary glands or uterus;
  • Severe liver dysfunction;
  • Liver tumors;
  • Idiopathic jaundice or itching during a previous pregnancy;
  • Herpes pregnant with a history of;
  • Otosclerosis with deterioration in previous pregnancies;
  • Severe disorders of fat metabolism;
  • Severe diabetes;
  • Transferred or existing thromboembolic diseases, arterial and venous thrombosis;
  • Severe diseases of the cardiovascular system;
  • Sickle cell anemia;
  • Severe arterial hypertension;
  • Dubin-Johnson syndrome;
  • Rotor syndrome.



Morgan Harding: “I have been taking Levlen since April 2007 for my gynecologist’s appointment. I still remain satisfied with it. Feeling great; performs not only its main function (protection against unwanted pregnancy) but also regulates my cycle (menstruation goes regularly without delays). Menstruation was delayed for 1-3 days when not taking this birth control. Thanks to this drug, the lower abdomen does not hurt. Previously, I have the experience to take painkillers during the 1-3 days of menstruation.”

Gracie Rhodes: “I take Levlen in order to prevent unwanted pregnancy. I prefer to first stand firmly on my feet, and then have children, which I can fully take care of.”

Eve Barrett: “I have chosen this birth control among many others. My gynecologist and I have conducted many screenings for making this selection. I am quite satisfied with the result. Be sure this drug doesn’t cause any side effects.”

Jodie Skinner: “The first-line choice of birth control. I like it, really like it. I control my cycle and protect from pregnancy.”